- Brain Health: Promotes cognitive health.
- Regulates Neural Signaling & Sensory Perception.
- Endocrine System: Health benefits related to the endocrine system.
- Heart Health:
- Immune System: Regulates Cellular Immune Response
- Cacao consumption up-regulates multiple intracellular signaling pathways involved in T cell activation and cellular immune response.
- Effects are noticeable within 2 hours. Greater gene expression is observed by the end of 1 week intervention.
- Cacao components inhibit MAPK activation
- T cell function is preserved and enhanced
Disease / Symptom Treatment
Title: Dark chocolate (70% cacao) effects human gene expression: Cacao regulates cellular immune response, neural signaling, and sensory perception
Author(s): Lee Berk, Kristin Bruhjell, Warren Peters, Peter Bastian, Evertt Lohman, Gurinder Bains, Jesusa Arevalo, and Steve Cole
Institution(s): Center for Health Promotion, Loma Linda University, Loma Linda, CA, Loma Linda University, Loma LInda, CA, Medicine and Psychiatry and Bio-behavioral Sciences, UCLA School of Medicine, Los Angeles, CA
Publication: The Federation of American Societies for Experimental Biology
Date: 20 Apr 2018
Abstract: Dark chocolate (70% Cacao) is a major source of flavonoid antioxidants, which appear to support cognitive, endocrine, and cardiovascular health benefits. However, the in vivo effects of cacao on human genome function are unknown. In a pilot feasibility experimental trial, we examined the effects acute and chronic cacao consumption on human gene expression in circulating blood cells.
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