- Broccoli sprout juice contains sulforaphanyl-amine.
- Broccoli sprouts are naturally enriched in glucoraphanin (GR) that is the biological precursor of the anticancer compound sulforaphane (SFN).
- Anti-cancer (anticancer)
- Prostate Health
Disease / Symptom Treatment
- Cancer Treatment / Prevention: Medicinal vegetables such as broccoli and their derivative phyto-compounds are being increasingly recognized as useful complementary treatments for cancer. Indole-3-carbinol (I3C), a natural phytochemical found in cruciferous vegetables (i.e. broccoli, cabbage or cauliflower), is considered a potential anticancer agent that prevents the development of certain types of tumors by activating tumor suppressor genes, genes involved in apoptosis and detoxification. I3C suppresses cell proliferation and induces apoptosis.
- Breast Cancer:
- Colorectal cancer:
- Prostate Cancer:
- Ovarian cancer:
- Cervix carcinoma:
- Hepatocarcinoma: (liver cancer)
Title: Glucoraphanin and sulforaphane evolution during juice preparation from broccoli sprouts
Author(s): Cristiano Bello, Mariateresa Maldini, Simona Baima, Cristina Scaccini, Fausta Natella
Institution(s): Food and Nutrition Research Centre, Via Ardeatina 546, 00178 Roma, Italy
Publication: Food Chemistry
Date: 19 June 2018
Abstract: Broccoli sprouts are considered functional food as they are naturally enriched in glucoraphanin (GR) that is the biological precursor of the anticancer compound sulforaphane (SFN). Due to its health promoting value, also broccoli sprout juice is becoming very popular. The present study aimed to quantitatively assess the conversion of GR to its hydrolysis products, SFN and SFN-nitrile, during the juice preparation process. We demonstrated that SFN plus SFN-nitrile yield from glucoraphanin is quite low (≈25%) and that some SFN is lost during the juice preparation partially due to the spontaneous conversion to sulforaphane-amine or conjugation to GSH and proteins naturally present in the juice. Our results demonstrate that the detection of the sole SFN free form does not provide reliable information about the real concentration of this functional compound in the juice.
Citations: ↩ ↩
Title: Phytotherapy of Prostate Cancer: How far are we?
Author(s): Guy-Armel Bounda
Publication: Clinical Oncology: Case Reports
Abstract: Prostate cancer (PCa) is the second most diagnosed cancer in men, principally affecting men over 50 years old, and is the fifth leading cause of cancer-related deaths in men worldwide. In recent years, the use of complementary and alternative medicine (CAM) has increased, especially among oncology patients. Treatment options are limited in androgen-independent prostate cancer. To reduce this tremendous health burden, new approaches have been directed toward extremes of the disease spectrum centering on strategies for prostate cancer prevention and for treating advanced androgen-independent cancers. Medicinal herbs and their derivative phytocompounds are being increasingly recognized as useful complementary treatments for cancer. Great number of clinical studies have reported the beneficial effects of herbal medicines on the survival, immune modulation, and quality of life (QOL) of cancer patients, when these herbal medicines are used in combination with conventional therapeutics. Although, tremendous efforts have been done in phytomedicine and phytotherapy, we still have a long way to go.